Silverman Lab

Simon Fraser University



Here is a sampling of microscopy images of our research.



Rich in data and full of beauty!



Cultured hippocampal neurons



Immunocytochemistry identifies dendrites with MAP2 (blue) and synapses with synapsin (red)



Cultured hippocampal neuron



Green fluorescent protein (GFP) fills one neuron in the field of view. The long, thin structures are axons and the shorter ones are dendrites. Note the spine heads on the dendrites.



Growth cone of a hippocampal neuron



Actin (red), microtubules (blue), dense core vesicles (green). An oldie but a goody - see Silverman et al., 2005 for more information.



Microtubules of a cultured hippocampal neuron



Near super-resolution imaging of tubulin staining.



Gorgeous, eh



GFP filled neuron - same cell pictured in a previous image



The cover photo for Mechanics of the Cell by David Boal



Nucleus (blue) Dendrites (red) Golgi apparatus (yellow) Dense-core vesicles (green)



Mouse hippocampus



H & E staining combined with Bielschowsky's stain



An experimental mistake, but a lovely picture



Cover photo, Molecular Biology of the Cell, Gan and Silverman 2015



Immunohistochemistry performed on the brain (cortex) of an Alzheimer's disease model mouse.



Nuclei (blue) Amyloid beta (red) a calcium channel (green). See Gan and Silverman 2015 for details.



Cultured hippocampal neuron



The axon initial segment is marked by an antibody to ankyrin in a cell expressing PSD95-GFP. Unpublished image.