[Please allow time for movie clip to load.] Alzheimer's peptides disrupt axonal transport of BDNF. Live imaging showing dense-core vesicle transport in control versus AßO-treated (18h, 0.5 uM) neurons. Note the significant difference between BDNF-mRFP vesicle flux in controls compared to AßO-treated neurons. For more information on these studies see reference #18.